Freiberg’s disease is a poorly understood disorder most commonly of the second metatarsal head in which a portion or all of the metatarsal head loses its structural integrity, which can lead to collapse of the joint surface and pain in the second metatarsophalangeal (MTP) joint. The process by which this loss of integrity and possible collapse happens is not well understood. Due to the fact that the affected area is often well circumscribed, the principle problem has traditionally been thought to be a vascular one. Basically, the blood supply to part of the bone of the metatarsal head for whatever reason is diminished or cut off. Freiberg’s disease, also called Freiberg’s infraction, is part of a group of disorders called osteochondroses, most of which affect pediatric patients, although Freiberg’s is more common in adults.


Freiberg’s is an epiphyseal disorder that ultimately ends up affecting the MTP joint. The second metatarsal head is most commonly affected, as it is the affected area in 68% of cases. The third and fourth metatarsal head account for 27% and 3% of cases, respectively. The first metatarsal head is never involved and the fifth only rarely. Bilateral involvement does occur in about 10% of cases.


Two classification schemes have been proposed, one more general for osteochondroses, one more specific to Freiberg’s.

  • Stage 1: involves intraarticular and periarticular soft tissue swelling.
  • Stage 2: shows some epiphyseal loss of contour, and the final stage is gradual replacement of the necrotic bone.
  • Stage 3: further collapse with some bone absorption
  • Stage 4: some fracture of the plantar hinge
  • Stage 5: MTP arthrosis

Patients often have pain over the affected metatarsal head with the sensation that they are walking on something hard. Later in the disease course, stiffness may be a central feature. Pain is often exacerbated by weight-bearing exercise.


Early in the course of the disease, patients can be put into a cast or boot with or without nonweight-bearing in an effort to decrease symptoms. Moving forward from that initial treatment, patients can be tried with any combination of a stiff insert, metatarsal pad, and rocker bottom shoe. Given that a tight heel cord could potentially increase forefoot loading and thereby worsen symptoms, stretching of the Achilles and/or gastrocnemius could be a part of a nonoperative treatment plan.

Operative treatment depends to some degree on how advanced the disease process is. For early stage disease, much like for osteonecrosis of the hip, core decompression has been advocated. Joint debridement is probably the most commonly performed procedure for this pathology, with removal of any and all loose bodies and excision of osteophytes. Various metatarsal osteotomies have been described in an effort to rotate the more normal plantar cartilage onto the end-loading surface of the metatarsal head. For end-stage disease, metatarsal head excision with or without interposition arthroplasty is often the treatment of choice.

Written by J. Turner Vosseler, MD Reviewed by Peter Deol, MD Last reviewed June 2015